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1.
Braz J Phys Ther ; 27(6): 100573, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38043159

RESUMO

BACKGROUND: Playing football involves a high risk of anterior cruciate ligament (ACL) injuries and these may affect knee function and activity level. OBJECTIVES: To measure changes in self-reported knee function, activity level, and satisfaction with knee function and activity level in female football players with or without an ACL-reconstructed knee. METHODS: Female football players, age 19.9 (SD 2.6) years, with either a primary ACL-reconstruction 1.6 (SD 0.7) years after ACL-reconstruction (n = 186) or no ACL injury (n = 113) were followed prospectively for five years. Self-reported data collected at baseline and follow-up included knee function (International Knee Documentation Committee Subjective Knee Form [IKDC-SKF]), activity level (Tegner Activity Scale), and satisfaction with knee function (Likert scale 1=happy; 7=unhappy) and activity level (1-10 scale). Information on any new ACL injury during the follow-up period was collected. RESULTS: Players with ACL-reconstruction at baseline who either did (n = 56) or did not (n = 130) sustain an additional ACL injury, and players with no injury at baseline who remained injury free (n = 101) had a lower Tegner score at follow-up. Players with additional ACL injury had lower IKDC-SKF score (mean difference: -11.4, 95% CI: -16.0, -6.7), and satisfaction with activity level (mean difference: -1.5, 95% CI: -2.3, -0.7) at follow-up. Players with no additional ACL injury had higher satisfaction with knee function (mean difference: 0.6, 95% CI: 0.3, 0.9) at follow-up. Players with no ACL injury had lower satisfaction with activity level (mean difference: -0.7, 95% CI: -1.1, -0.3) at follow-up. Players with additional ACL injury had larger decreases in all variables measured compared to the two other groups. CONCLUSION: Primary, and even more so additional, ACL injuries decreased self-reported knee function, activity level, and satisfaction with knee function and activity level in female football players.


Assuntos
Lesões do Ligamento Cruzado Anterior , Traumatismos em Atletas , Articulação do Joelho , Futebol , Adulto , Feminino , Humanos , Adulto Jovem , Lesões do Ligamento Cruzado Anterior/fisiopatologia , Seguimentos , Articulação do Joelho/fisiopatologia , Autorrelato , Futebol/lesões , Traumatismos em Atletas/fisiopatologia
2.
Sci Rep ; 12(1): 13509, 2022 08 05.
Artigo em Inglês | MEDLINE | ID: mdl-35931722

RESUMO

Each year 65% of young athletes and 25% of physically active adults suffer from at least one musculoskeletal injury that prevents them from continuing with physical activity, negatively influencing their physical and mental well-being. The treatment of musculoskeletal injuries with the adhesive elastic kinesiology tape (KT) decreases the recovery time. Patients can thus recommence physical exercise earlier. Here, a novel KT based on auxetic structures is proposed to simplify the application procedure and allow personalization. This novel KT exploits the form-fitting property of auxetics as well as their ability to simultaneously expand in two perpendicular directions when stretched. The auxetic contribution is tuned by optimizing the structure design using analytical equations and experimental measurements. A reentrant honeycomb topology is selected to demonstrate the validity of the proposed approach. Prototypes of auxetic KT to treat general elbow pains and muscle tenseness in the forearm are developed.


Assuntos
Atletas , Traumatismos em Atletas/psicologia , Traumatismos em Atletas/terapia , Fita Atlética , Cinesiologia Aplicada/métodos , Sistema Musculoesquelético/lesões , Adulto , Atletas/psicologia , Traumatismos em Atletas/fisiopatologia , Exercício Físico/fisiologia , Antebraço/fisiopatologia , Humanos , Cinesiologia Aplicada/educação , Ferimentos e Lesões/fisiopatologia , Ferimentos e Lesões/psicologia , Ferimentos e Lesões/terapia
3.
Int J Sports Physiol Perform ; 17(5): 761-767, 2022 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-35226865

RESUMO

PURPOSE: Determine the impact of preseason and between-seasons changes in individual physical performance on injury risk in elite junior Australian football players and if injuries sustained during a season impact subsequent-season performance improvement. METHODS: This prospective cohort study assessed individual performance measures (sprint speed, jump, agility, and aerobic endurance) during preseason over 4 consecutive seasons. Injury status (injured/not injured) was tracked weekly to determine the relationship between individual performance and in-season injury occurrence. Mixed models were used to determine the relationship between physical performance and injury, and the effect of injury on physical performance improvement. RESULTS: A total of 206 players played 2 consecutive seasons and were included (17.6 y, 181.9 cm, 75.7 kg). Faster players during preseason experienced higher injury incidence (injuries/season) during that playing season (incidence rate ratio = 0.127; P = .034). Injury incidence was not influenced by between-seasons change in any performance measure. Players injured during their first season maintained their aerobic fitness, which declined in noninjured players (d = 0.39; P = .013). Players who sustained a lower-limb injury during their first season saw smaller improvements in sprint speed than players who did not get injured (d = 0.39; P = .035). CONCLUSION: Faster players experience higher injury incidence than slower players and may require specific prevention interventions. Players who experience a lower-limb injury during the playing season do not improve sprint speed between seasons to the same extent as players who do not get injured, highlighting the need for targeted high-speed running ability development as part of rehabilitation.


Assuntos
Esportes de Equipe , Humanos , Atletas , Traumatismos em Atletas/epidemiologia , Traumatismos em Atletas/etiologia , Traumatismos em Atletas/fisiopatologia , Austrália/epidemiologia , Estudos de Coortes , Estudos Prospectivos , Estações do Ano
4.
Eur J Appl Physiol ; 122(2): 357-369, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34729636

RESUMO

PURPOSE: Cortical mechanisms may contribute to weakness in participants with previous hamstring strain injury. This study aims to examine intra-cortical inhibition (SICI) and corticospinal excitability in previously injured participants. METHODS: In this cross-sectional study, TMS was used to examine SICI, silent period, silent period: MEP ratios and area under the stimulus response curve in the biceps femoris and medial hamstrings. Comparisons were made between participants with (n = 10) and without (n = 10) previous hamstring strain injury. Motor threshold and isometric knee flexor strength were also compared between participants and the relationship between strength and SICI in control and previously injured participants was examined. RESULTS: Isometric knee flexor strength was lower in previously injured limbs compared with control limbs (mean difference = - 41 Nm (- 26%) [95% CI = - 80 to - 2 Nm], p = 0.04, Cohen's d = - 1.27) and contralateral uninjured limbs (mean difference = - 23 Nm (- 17%), [95% CI = - 40 to - 6 Nm], p = 0.01, Cohen's d = - 0.57). Previously injured limbs exhibited smaller responses to paired pulse stimulation (i.e. greater levels of SICI) in the biceps femoris compared with control limbs (mean difference = - 19%, [95% CI = - 34 to - 5%], p = 0.007, Cohen's d = - 1.33). Isometric knee flexor strength was associated with the level of SICI recorded in the biceps femoris in previously injured participants (coefficient = 23 Nm [95% CI = 7-40 Nm], adjusted R2 = 0.31, p = 0.01). There were no differences in markers of corticospinal excitability between previously injured and control limbs (all p > 0.24, all Cohen's d < 0.40). CONCLUSION: Athletes with previous injury in the biceps femoris exhibit increased SICI in this muscle compared with control participants. Increased SICI is related to lower levels of hamstring strength, and rehabilitation programs targeting the removal of intra-cortical inhibition should be considered.


Assuntos
Traumatismos em Atletas/fisiopatologia , Traumatismos em Atletas/reabilitação , Músculos Isquiossurais/lesões , Debilidade Muscular/fisiopatologia , Inibição Neural/fisiologia , Estimulação Magnética Transcraniana , Estudos Transversais , Eletromiografia , Humanos , Masculino , Adulto Jovem
5.
Laryngoscope ; 132(2): 436-442, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34363397

RESUMO

OBJECTIVES/HYPOTHESIS: To 1) characterize vestibular-evoked myogenic potential responses in children and young adults with sports-related concussion (SRC) histories as compared with a normal healthy control group, and 2) correlate VEMP characteristics to SRC/sport history outcomes. STUDY DESIGN: Prospective cohort study. METHODS: Seventy-six children and young adults with and without a history of SRC received cervical and ocular VEMP testing using a 500 Hz tone burst air conduction stimuli. VEMP response parameters (response rates, peak latencies, and peak-to-peak amplitudes) were assessed. Other clinical vestibular measures were performed. In the SRC group, sport history outcomes including number of SRC sustained over a lifetime, years of playing contact sports, and length of time playing contact sports were collected via in-person questionnaire. RESULTS: Children and young adults with SRC had significantly reduced oVEMP responses and peak-to-peak amplitudes and greater amplitude response asymmetries between left and right ear. There was no effect of group on cVEMP findings. A greater frequency of SRCs sustained throughout a lifetime, a greater number of contact sports played, and a longer duration of playing a contact sport correlated with significantly poorer VEMP response characteristics. CONCLUSIONS: Our results suggest that SRC and repeated subclinical head impact events have an effect on oVEMP outcomes. SRC may affect the utricle, superior vestibular nerve, and/or brainstem-mediated vestibular-ocular-reflex pathway. The prevalence of post-concussion-related dizziness is becoming increasingly common in a pediatric-otology clinic, thus performing VEMP testing in youth post-SRC provides an objective, noninvasive, and cost-effective method for monitoring the effects of sports-related impact on the vestibular system and related neural pathways. LEVEL OF EVIDENCE: 3 Laryngoscope, 132:436-442, 2022.


Assuntos
Traumatismos em Atletas/fisiopatologia , Concussão Encefálica/fisiopatologia , Potenciais Evocados Miogênicos Vestibulares , Adolescente , Adulto , Criança , Feminino , Humanos , Masculino , Estudos Prospectivos , Adulto Jovem
6.
Ann N Y Acad Sci ; 1507(1): 121-132, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34480369

RESUMO

Dysregulation of cardiovascular autonomic control is gaining recognition as a prevailing consequence of concussion injury. Characterizing the presence of autonomic dysfunction in concussed persons is inconsistent and conventional metrics of autonomic function cannot differentiate the presence/absence of injury. Mayer wave (MW) activity originates through baroreflex adjustments to blood pressure (BP) oscillations that appear in the low-frequency (LF: 0.04-0.15 Hz) band of the BP and heart rate (HR) power spectrum after a fast Fourier transform. We prospectively explored MW activity (∼0.1 Hz) in 19 concussed and 19 noninjured athletes for 5 min while seated at rest within 48 h and 1 week of injury. MW activity was derived from the LF band of continuous digital electrocardiogram and beat-to-beat BP signals (LFHR, LF-SBP, MWHR, and MW-SBP, respectively); a proportion between MWBP and MWHR was computed (cMW). At 48 h, the concussion group had a significantly lower MWBP and cMW than controls; these differences were gone by 1 week. MWHR, LFHR, and LF-SBP were not different between groups at either visit. Attenuated sympathetic vasomotor tone was present and the central autonomic mechanisms regulating MW activity to the heart and peripheral vasculature became transiently discordant early after concussion with apparent resolution by 1 week.


Assuntos
Traumatismos em Atletas/fisiopatologia , Sistema Nervoso Autônomo/fisiopatologia , Pressão Sanguínea/fisiologia , Concussão Encefálica/fisiopatologia , Eletrocardiografia/métodos , Frequência Cardíaca/fisiologia , Adolescente , Traumatismos em Atletas/diagnóstico , Concussão Encefálica/diagnóstico , Estudos de Coortes , Eletrocardiografia/tendências , Feminino , Humanos , Masculino , Universidades/tendências , Adulto Jovem
7.
Med Sci Sports Exerc ; 54(2): 307-312, 2022 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-34559729

RESUMO

INTRODUCTION: Physical activity (PA) and mental activity (MA) postconcussion has received renewed attention to improve concussion management; however, most protocols start after several days and do not assess the acute window. Therefore, the purpose of this study was to assess PA and MA in the first 48 h postconcussion on the time to symptom-free status and return to play. METHODS: We recruited 78 NCAA Division I athletes (male, 51.3%; age, 19.6 ± 1.4 yr; height, 173.7 ± 11.5 cm; weight, 80.1 ± 23.2 kg) who were diagnosed with a sports-related concussion. Participants completed a 0-5 PA and MA scale daily until fully cleared for return to participation (mean, 15.1 ± 6.9 d). A quadratic model regression assessed PA and MA over the first 2 d (acute) postconcussion on to time to symptom-free status and return to play. RESULTS: The overall model was significant for both time to symptom free (r2 = 0.27, P = 0.004) and return to play (r2 = 0.23, P = 0.019). Reported PA was the only significant predictor for time to symptom-free (P = 0.002) and return-to-participation (P = 0.006) day. Reported MA was not associated either outcome. CONCLUSIONS: The primary finding of this study was that mild to moderate PA acutely postconcussion was associated with reduced time to symptom free and return to participation as opposed to either lower or higher levels of PA. Conversely, acute MA was not associated with recovery outcomes. These results further elucidate the role of postconcussion PA.


Assuntos
Traumatismos em Atletas/fisiopatologia , Traumatismos em Atletas/psicologia , Concussão Encefálica/fisiopatologia , Concussão Encefálica/psicologia , Cognição/fisiologia , Exercício Físico , Volta ao Esporte , Adolescente , Adulto , Traumatismos em Atletas/diagnóstico , Concussão Encefálica/diagnóstico , Exercício Físico/fisiologia , Exercício Físico/psicologia , Feminino , Humanos , Modelos Lineares , Estudos Longitudinais , Masculino , Estudos Prospectivos , Volta ao Esporte/fisiologia , Volta ao Esporte/psicologia , Autorrelato , Adulto Jovem
8.
Ann Biomed Eng ; 49(12): 3438-3451, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34853920

RESUMO

Sex, head and neck posture, and cervical muscle preparation are contributing factors in the severity of head and neck injuries. However, it is unknown how these factors modulate the head kinematics. In this study, twenty-four (16 male and 8 female) participants experienced 50 impulsive forces to their heads with and without an acoustic warning. Female participants demonstrated a 71 ms faster (p = 0.002) muscle activation onset compared to males after warning. The magnitude of muscle activation was not significant between sexes. Females exhibited 21% (p < 0.008) greater peak angular velocity in all force directions and 18% (p < 0.04) greater peak angular acceleration in sagittal plane compared to males. Females exhibited 15% (p = 0.03) greater peak linear acceleration compared to males only in sagittal flexion. Preparation attenuated head kinematics significantly (p < 0.03) in 11 out of 18 investigated head kinematics for both sexes. A warning eliciting a startle response 420 ms prior to the impact resulted in significant attenuation of all measured head kinematics in sagittal extension (p < 0.037). In conclusion, both sex and warning type were significant factors in head kinematics. These data provide insight into the complex relationship of muscle activation and sex, and may help identify innovative strategies to reduce head and neck injury risk in sports.


Assuntos
Traumatismos Craniocerebrais/fisiopatologia , Lesões do Pescoço/fisiopatologia , Músculos do Pescoço/fisiologia , Reflexo de Sobressalto/fisiologia , Aceleração , Acústica , Fatores Etários , Traumatismos em Atletas/fisiopatologia , Fenômenos Biomecânicos , Eletromiografia , Feminino , Humanos , Masculino , Contração Muscular , Pescoço/anatomia & histologia , Músculos do Pescoço/anatomia & histologia , Postura/fisiologia
9.
Hum Brain Mapp ; 42(18): 5814-5826, 2021 12 15.
Artigo em Inglês | MEDLINE | ID: mdl-34643005

RESUMO

Concussion is associated with acute disturbances in brain function and behavior, with potential long-term effects on brain health. However, it is presently unclear whether there are sex differences in acute and long-term brain recovery. In this study, magnetic resonance imaging (MRI) was used to scan 61 participants with sport-related concussion (30 male, 31 female) longitudinally at acute injury, medical clearance to return to play (RTP), and 1-year post-RTP. A large cohort of 167 controls (80 male, 87 female) was also imaged. Each MRI session assessed cerebral blood flow (CBF), along with white matter fractional anisotropy (FA) and mean diffusivity (MD). For concussed athletes, the parameters were converted to difference scores relative to matched control subgroups, and partial least squares modeled the main and sex-specific effects of concussion. Although male and female athletes did not differ in acute symptoms or time to RTP , all MRI measures showed significant sex differences during recovery. Males had greater reductions in occipital-parietal CBF (mean difference and 95%CI: 9.97 ml/100 g/min, [4.84, 15.12] ml/100 g/min, z = 3.73) and increases in callosal MD (9.07 × 10-5 , [-14.14, -3.60] × 10-5 , z = -3.46), with greatest effects at 1-year post-RTP. In contrast, females had greater reductions in FA of the corona radiata (16.50 × 10-3 , [-22.38, -11.08] × 10-3 , z = -5.60), with greatest effects at RTP. These findings provide new insights into how the brain recovers after a concussion, showing sex differences in both the acute and chronic phases of injury.


Assuntos
Traumatismos em Atletas/diagnóstico por imagem , Concussão Encefálica/diagnóstico por imagem , Circulação Cerebrovascular/fisiologia , Imageamento por Ressonância Magnética , Caracteres Sexuais , Substância Branca/diagnóstico por imagem , Adolescente , Adulto , Traumatismos em Atletas/patologia , Traumatismos em Atletas/fisiopatologia , Concussão Encefálica/patologia , Concussão Encefálica/fisiopatologia , Imagem de Tensor de Difusão , Feminino , Humanos , Estudos Longitudinais , Masculino , Recuperação de Função Fisiológica/fisiologia , Substância Branca/patologia , Adulto Jovem
10.
J Orthop Sports Phys Ther ; 51(10): 478-491, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34592831

RESUMO

OBJECTIVE: To identify the most suitable existing generic and condition-specific health-related quality of life (HRQoL) patient-reported outcome measures (PROMs) for active youth with and without a musculoskeletal injury, based on measurement properties, interpretability, and feasibility. DESIGN: Systematic review of clinimetrics. LITERATURE SEARCH: We searched MEDLINE, Embase, CINAHL, SPORTDiscus, PsycINFO, and Scopus from inception to April 30, 2020. STUDY SELECTION CRITERIA: Records with original data describing the evaluation of a PROM or PROM subscale in active youth (15-24 years old) with or without a musculoskeletal injury were included. Non-English studies and those including individuals with a cognitive, developmental, or systemic condition were excluded. DATA SYNTHESIS: This review was conducted according to the COSMIN user manual for systematic reviews of PROMs and the PRISMA guidelines. The COSMIN user manual guided our measurement property evaluation and interpretability and feasibility description. RESULTS: Of 6931 potential records, 21 studies were included. Eleven generic and 7 condition-specific PROMs were identified. No PROM received a final COSMIN recommendation of "A" because all lacked sufficient content validity. The 8-item Disablement in the Physically Active scale-mental summary component Short Form (DPA-MSC SF-8), Quality of Life Survey, and Functional Arm Scale for Throwers (FAST) were the most suitable existing PROMs, given their high-quality evidence for sufficient structural validity and internal consistency. CONCLUSION: No definitively robust PROM for measuring generic or condition-specific HRQoL of active youth was identified. Until one exists, we recommend the DPA-MSC SF-8, the Quality of Life Survey, or the FAST and applying mixed methods to best characterize the HRQoL of active youth. J Orthop Sports Phys Ther 2021;51(10):478-491. doi:10.2519/jospt.2021.10412.


Assuntos
Traumatismos em Atletas/fisiopatologia , Traumatismos em Atletas/psicologia , Medidas de Resultados Relatados pelo Paciente , Qualidade de Vida , Adolescente , Criança , Humanos
12.
Ann Biomed Eng ; 49(10): 2814-2826, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34549342

RESUMO

Repeated head impact exposure and concussions are common in American football. Identifying the factors associated with high magnitude impacts aids in informing sport policy changes, improvements to protective equipment, and better understanding of the brain's response to mechanical loading. Recently, the Stanford Instrumented Mouthguard (MiG2.0) has seen several improvements in its accuracy in measuring head kinematics and its ability to correctly differentiate between true head impact events and false positives. Using this device, the present study sought to identify factors (e.g., player position, helmet model, direction of head acceleration, etc.) that are associated with head impact kinematics and brain strain in high school American football athletes. 116 athletes were monitored over a total of 888 athlete exposures. 602 total impacts were captured and verified by the MiG2.0's validated impact detection algorithm. Peak values of linear acceleration, angular velocity, and angular acceleration were obtained from the mouthguard kinematics. The kinematics were also entered into a previously developed finite element model of the human brain to compute the 95th percentile maximum principal strain. Overall, impacts were (mean ± SD) 34.0 ± 24.3 g for peak linear acceleration, 22.2 ± 15.4 rad/s for peak angular velocity, 2979.4 ± 3030.4 rad/s2 for peak angular acceleration, and 0.262 ± 0.241 for 95th percentile maximum principal strain. Statistical analyses revealed that impacts resulting in Forward head accelerations had higher magnitudes of peak kinematics and brain strain than Lateral or Rearward impacts and that athletes in skill positions sustained impacts of greater magnitude than athletes in line positions. 95th percentile maximum principal strain was significantly lower in the observed cohort of high school football athletes than previous reports of collegiate football athletes. No differences in impact magnitude were observed in athletes with or without previous concussion history, in athletes wearing different helmet models, or in junior varsity or varsity athletes. This study presents novel information on head acceleration events and their resulting brain strain in high school American football from our advanced, validated method of measuring head kinematics via instrumented mouthguard technology.


Assuntos
Traumatismos em Atletas/fisiopatologia , Encéfalo/fisiologia , Traumatismos Craniocerebrais/fisiopatologia , Protetores Bucais , Equipamentos Esportivos , Telemetria/instrumentação , Adolescente , Fenômenos Biomecânicos , Futebol Americano , Cabeça , Humanos , Masculino , Instituições Acadêmicas , Estados Unidos , Dispositivos Eletrônicos Vestíveis
14.
Scand J Med Sci Sports ; 31(12): 2187-2197, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34423879

RESUMO

Cross-country eventing is one of the highest-risk sporting activities for serious injury outcomes. This study investigated relationships between fall characteristics and high-risk falls at jumps in cross-country eventing. A video analysis protocol was systematically developed to analyze 87 video recordings of high-risk rider falls; defined as when the rider's head impacted the ground and/or where there was potential horse impact with the rider. Falls were classified according to competition type, jump type, horse-related, and rider-related factors. At least one high-risk fall characteristic was observed in 45 of 87 examined falls. Multivariable best subsets regression identified five independent variables explaining 38.4% of the variance in the number of high-risk falls. Increased likelihood of high-risk falls was associated with continuation of horse direction or speed upon rider ground impact, higher jump approach speed, changes in rider body posture upon landing, rider air jacket usage, and reduced rider fall time. The Eventing Fall Assessment Instrument (EFAI) video analysis protocol (attached as supplementary material) facilitated systematic examination of multiple characteristics associated with high-risk falls and identified likely influential characteristics. Based on EFAI and subsequent data analyses, findings suggest optimized approach speed for correct striding and take-off; jump design to enable run-out; and rider training could help reduce the occurrence of high-risk falls. Air jacket usage and their design characteristics warrant further investigation.


Assuntos
Acidentes por Quedas , Traumatismos em Atletas/fisiopatologia , Comportamento Competitivo/fisiologia , Cavalos , Gravação em Vídeo , Acidentes por Quedas/prevenção & controle , Animais , Traumatismos em Atletas/prevenção & controle , Feminino , Humanos , Masculino , Análise Multivariada , Postura/fisiologia , Roupa de Proteção , Fatores de Risco , Fatores Sexuais , Estudos de Tempo e Movimento
15.
Sci Rep ; 11(1): 13838, 2021 07 05.
Artigo em Inglês | MEDLINE | ID: mdl-34226626

RESUMO

Little is known about the neuropsychiatric and neurophysiological differences that characterize abnormal recovery following a concussion. The present study aimed to investigate the psycho-affective, cognitive, and neurophysiological profiles of symptomatic, slow-to-recover, concussed athletes, asymptomatic concussed athletes, and control athletes. Seventy-eight athletes (26 symptomatic, 26 asymptomatic, 26 control) completed the Beck Depression Inventory-II, Profile of Mood States, and 2-Back task. Additionally, event-related brain potentials were recorded during an experimental three-stimulus visual Oddball paradigm. Compared to asymptomatic and control groups, the symptomatic group reported greater depression symptoms and negatively altered mood states. Symptomatic athletes also exhibited poorer cognitive performance on the 2-Back task, indicated by more errors and slower reaction time. ERP analyses indicated prolonged P3b latency for both symptomatic and asymptomatic groups, but symptomatic athletes also exhibited reduced P3b amplitude compared to both asymptomatic and control groups. For the asymptomatic group, correlations were observed between time since last concussion and functioning, but no relations were observed within the symptomatic group for any measure. The current findings provide valuable information regarding the psycho-affective, cognitive, and neurophysiological profiles of athletes with and without persistent symptoms following a concussion and highlight the need to assess and treat symptomatic, slow-to-recover athletes from a multidimensional and integrative perspective.


Assuntos
Atletas , Traumatismos em Atletas/fisiopatologia , Concussão Encefálica/fisiopatologia , Encéfalo/fisiopatologia , Adulto , Traumatismos em Atletas/diagnóstico por imagem , Encéfalo/diagnóstico por imagem , Concussão Encefálica/diagnóstico por imagem , Cognição/fisiologia , Eletroencefalografia , Potenciais Evocados P300/fisiologia , Feminino , Humanos , Masculino , Testes Neuropsicológicos , Adulto Jovem
16.
Ann Biomed Eng ; 49(10): 2791-2804, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34231091

RESUMO

Wearable devices have been shown to effectively measure the head's movement during impacts in sports like American football. When a head impact occurs, the device is triggered to collect and save the kinematic measurements during a predefined time window. Then, based on the collected kinematics, finite element (FE) head models can calculate brain strain and strain rate, which are used to evaluate the risk of mild traumatic brain injury. To find a time window that can provide a sufficient duration of kinematics for FE analysis, we investigated 118 on-field video-confirmed football head impacts collected by the Stanford Instrumented Mouthguard. The simulation results based on the kinematics truncated to a shorter time window were compared with the original to determine the minimum time window needed for football. Because the individual differences in brain geometry influence these calculations, we included six representative brain geometries and found that larger brains need a longer time window of kinematics for accurate calculation. Among the different sizes of brains, a pre-trigger time of 40 ms and a post-trigger time of 70 ms were found to yield calculations of brain strain and strain rate that were not significantly different from calculations using the original 200 ms time window recorded by the mouthguard. Therefore, approximately 110 ms is recommended for complete modeling of impacts for football.


Assuntos
Encéfalo/fisiologia , Futebol Americano/lesões , Modelos Biológicos , Telemetria/métodos , Aceleração , Traumatismos em Atletas/fisiopatologia , Fenômenos Biomecânicos , Lesões Encefálicas/fisiopatologia , Feminino , Análise de Elementos Finitos , Cabeça , Humanos , Masculino , Protetores Bucais , Equipamentos Esportivos , Telemetria/instrumentação , Estados Unidos , Dispositivos Eletrônicos Vestíveis
17.
Scand J Med Sci Sports ; 31(10): 1908-1913, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34233053

RESUMO

Football players are at increased risk of neurodegeneration, the likely consequence of repetitive mechanical trauma caused by heading the ball. However, to what extent a history of heading the ball affects cerebral blood flow (CBF) regulation and its potential relationship to cognitive impairment is unknown. To address this, we recruited 16 concussion-free male amateur football players (age: 25 ± 6 y) with a history of heading the ball (18 ± 6 y) and 18 sex, age, education, and activity-matched controls with no prior history of contact sport participation or concussion. Cerebral perfusion was measured at rest and in response to both hyper/hypocapnia to determine cerebrovascular reactivity to carbon dioxide (CVRCO2HYPER/HYPO ) using transcranial Doppler ultrasound and capnography, with the sum reflecting the cerebral vasomotor range. Cognition and visuomotor coordination were assessed using the Montreal cognitive assessment (MoCA) and the Grooved Pegboard Dexterity Test (GPD), respectively. While no differences in cerebral perfusion were observed (p = 0.938), CVRCO2HYPER/HYPO (p = 0.038/p = 0.025), cerebral vasomotor range (p = 0.002), MoCA (p = 0.027), and GPD performance (dominant hand, P ≤ 0.001) were consistently lower in the players compared to controls. These findings are the first to demonstrate that CBF regulation and cognition are collectively impaired in male football players with history of heading the ball, which may contribute to neurodegeneration.


Assuntos
Traumatismos em Atletas/fisiopatologia , Concussão Encefálica/fisiopatologia , Circulação Cerebrovascular/fisiologia , Transtornos Cognitivos/fisiopatologia , Futebol/lesões , Futebol/fisiologia , Adulto , Estudos Transversais , Humanos , Masculino , Adulto Jovem
18.
J Neurotrauma ; 38(22): 3097-3106, 2021 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-34314246

RESUMO

Concussion is a major health concern, making it critical to identify factors that influence risk and resilience. The salience network (SN) likely plays a key role in concussion risk, given its roles in orienting attention, functional adaptability, and interoceptive awareness. The SN's functions are thought to be mediated through causal control of other networks, including the default mode network (DMN) and executive control network (ECN). It was therefore hypothesized that the SN of at-risk individuals would have altered functional and structural connectivity with the DMN and ECN. For this prospective study, 167 university athletes had baseline clinical assessments and magnetic resonance imaging scans and were monitored for the rest of their varsity career, with any concussions recorded. Athletes concussed in the same season as imaging (CSS; n = 17) and those concussed in later seasons (CLS; n = 15) were matched to controls that were not concussed after imaging. Functional connectivity and white matter fractional anisotropy (FA) were compared between concussed and control groups. Prior to injury, CSS athletes had significantly elevated total symptom severity scores, elevated SN-DMN functional connectivity and reduced FA of connecting white matter tracts, whereas CLS athletes showed no significant clinical or imaging effects. These findings provide new insights into the neurobiology of concussion risk and resilience, as indices of SN-DMN network connectivity are associated with short-term but not long-term concussion risk.


Assuntos
Traumatismos em Atletas/etiologia , Traumatismos em Atletas/fisiopatologia , Concussão Encefálica/etiologia , Concussão Encefálica/fisiopatologia , Resiliência Psicológica/fisiologia , Adolescente , Anisotropia , Traumatismos em Atletas/diagnóstico por imagem , Concussão Encefálica/diagnóstico por imagem , Mapeamento Encefálico , Estudos de Casos e Controles , Função Executiva/fisiologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Estudos Prospectivos , Substância Branca/diagnóstico por imagem , Adulto Jovem
19.
Med Sci Sports Exerc ; 53(11): 2419-2424, 2021 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-34081057

RESUMO

PURPOSE: It is unknown why some athletes develop patellar tendinopathy and others do not, even when accounting for similar workloads between individuals. Genetic differences between these two populations may be a contributing factor. The purpose of this work was to screen the entire genome for genetic markers associated with patellar tendinopathy. METHODS: Genome-wide association (GWA) analyses were performed utilizing data from the Kaiser Permanente Research Board (KPRB) and the UK Biobank. Patellar tendinopathy cases were identified based on electronic health records from KPRB and UK Biobank. GWA analyses from both cohorts were tested for patellar tendinopathy using a logistic regression model adjusting for sex, height, weight, age, and race/ethnicity using allele counts for single nucleotide polymorphisms. The data from the two GWA studies (KPRB and UK Biobank) were combined in a meta-analysis. RESULTS: There were a total of 1670 cases of patellar tendinopathy and 293,866 controls within the two cohorts. Two single nucleotide polymorphisms located in the intron of the cytochrome c oxidase assembly factor 1 (COA1) gene showed a genome-wide significant association in the meta-analysis. CONCLUSIONS: Genetic markers in COA1 seem to be associated with patellar tendinopathy and are potential risk factors for patellar tendinopathy that deserve further validation regarding molecular mechanisms.


Assuntos
Traumatismos em Atletas/genética , Complexo IV da Cadeia de Transporte de Elétrons/genética , Estudo de Associação Genômica Ampla , Ligamento Patelar/lesões , Polimorfismo de Nucleotídeo Único , Tendinopatia/genética , Traumatismos em Atletas/fisiopatologia , Feminino , Marcadores Genéticos , Humanos , Masculino , Pessoa de Meia-Idade
20.
Ann Biomed Eng ; 49(10): 2886-2900, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34184145

RESUMO

Impacts to the back of the head due to rearward falls, also referred to as "backfall" events, represent a common source of TBI for athletes and soldiers. A new experimental apparatus is described for replicating the linear and rotational kinematics of the head during backfall events. An anthropomorphic test device (ATD) with a head-borne sensor suite was configured to fall backwards from a standing height, inducing contact between the rear of the head and a ground surface simulant. A pivoting swing arm and release strap were used to generate consistent and realistic head kinematics. Backfall experiments were performed with the ATD fitted with an American football helmet and the resulting linear and rotational head kinematics, as well as calculated injury metrics, compared favorably with those of football players undergoing similar impacts during games or play reconstructions. This test method complements existing blunt impact helmet performance experiments, such as drop tower and pneumatic ram test methods, which may not be able to fully reproduce head-neck-torso kinematics during a backfall event.


Assuntos
Acidentes por Quedas , Traumatismos em Atletas/fisiopatologia , Traumatismos Craniocerebrais/fisiopatologia , Futebol Americano/lesões , Modelos Biológicos , Telemetria/instrumentação , Dispositivos Eletrônicos Vestíveis , Aceleração , Fenômenos Biomecânicos , Cabeça , Dispositivos de Proteção da Cabeça , Humanos , Masculino , Protetores Bucais , Rotação
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